The Man With Two Brains (1983)

The whole setup of this dark screwball comedy will feel a tad misogynistic to some: Steve Martin plays a mad neurosurgeon, Dr. Michael Hfuhruhurr, who falls in love with femme fatale Dolores Benedict (Kathleen Turner), then builds up resentment as she declines to consummate their marriage.

Meanwhile, he falls in love with a disembodied brain, Anne (voiced by Sissy Spacek) and begins searching for a body in which to house her. Along the way, he roots for one attractive woman to die, and ponders killing another. It all crescendoes in a joke at the expense of compulsive eaters.

It’s not in the same league as The Jerk, a previous collaboration between Steve Martin and director Carl Reiner, but it has some very funny scenes.